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dimeric moiety may be attached to the substituted tetracycline through a chain of from 1-30 atoms. PAO1 cells at the exponential growth phase were resistant to azithromycin. In particular, cyklokapron cost in one aspect the invention pertains to methods for using the novel substituted tetracycline compounds of the invention for regulating expression of a target nucleic acid sequence that is under transcriptional control of a tetracycline-responsive promoter element (TRE) in a cell of a subject?
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